ARMS Antibody

Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9ULH0].
KIDINS220
kinase D-interacting substrate 220kDa
Kinase D-interacting substrate of 220 kDa
:  ankyrin repeat-rich membrane spanning ankyrin repeat-rich membrane-spanning protein ARMS kinase D-interacting substrate, 220kDa truncated KIDINS220
Product
Specifications
Ordering Information
Human
WB, IP
Between 1400 and 1450
100
$339
$229
$99
Human
IP
Between 1721 and 1771
100
$339
$99
Human
100
Includes: 1 each of A303-002A and A303-003A
$472
Includes: 1 each of A303-002A and A303-003A