p150glued Antibody

p150glued is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. The p150glued subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus [taken from NCBI Entrez Gene (Gene ID: 1639)].
DCTN1
dynactin subunit 1
Dynactin subunit 1
:  150 kDa dynein-associated polypeptide DAP-150 DP-150 dynactin 1 (p150, Glued (Drosophila) homolog) dynactin 1 (p150, glued homolog, Drosophila) P135 p150 glued homolog (Drosophila) p150-glued
Product
Specifications
Ordering Information
Human
IP
Between 1100 to 1150
100
$339
$99
Human, Mouse
WB, IP
Between 1228 to 1278
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A303-071A and A303-072A
$472
Includes: 1 each of A303-071A and A303-072A