ZEB1 Antibody

ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.
ZEB1
zinc finger E-box binding homeobox 1
Zinc finger E-box-binding homeobox 1
:  AREB6 BZP delta-crystallin enhancer binding factor 1 DELTAEF1 FECD6 negative regulator of IL2 NIL2A NIL-2-A NIL-2-A zinc finger protein posterior polymorphous corneal dystrophy 3 PPCD3 TCF8 TCF-8 Transcription factor 8 transcription factor 8 (represses interleukin 2 expression) ZEB Zfhep Zfhx1a zinc finger homeodomain enhancer-binding protein More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 850 and 900
100
$339
$229
$99
Human, Mouse
WB, IP, IHC-P
Between 1074 and 1124
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A301-921A and A301-922A
$472
Includes: 1 each of A301-921A and A301-922A
Human, Mouse
IHC-P
Between 1074 and 1124
100
$360
$99