Sirt1 Antibody

Sirt1 is one of seven members of the sirtuin family of proteins that are homologous to the yeast silent information regulator 2 (Sir2), a NAD+-dependent protein deacetylase that plays a role in lifespan in lower eukaryotes. The sirtuins are diverse in their cellular functions, and are important to the regulation of oxidative stress, and metabolism. Sirt 1 is localized to the nucleus and possesses deacetylase activity. Sirt 1 has been shown to be able to deacetylate p53, Ku70, NF-kappaB and forkhead proteins to mediate cellular resistance to stress.
SIRT1
sirtuin 1
NAD-dependent protein deacetylase sirtuin-1
:  hSIR2 hSIRT1 regulatory protein SIR2 homolog 1 SIR2 SIR2alpha SIR2L1 SIR2-like protein 1 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1 sirtuin type 1 More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 25 and 75
100
$339
$229
$99
Human
WB, IP, PLA
Between 700 and C-term
100
$339
$229
$99
Human
100
Includes: 1 each of A300-687A and A300-688A
$472
Includes: 1 each of A300-687A and A300-688A