ROCK1 Antibody

Rho-associated protein kinase 1 (ROCK1), also known as Rho kinase beta, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK1 shares an overall 65% homology in amino acid sequence with ROCK2. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.
ROCK1
Rho associated coiled-coil containing protein kinase 1
Rho-associated protein kinase 1
:  p160 ROCK-1 p160ROCK renal carcinoma antigen NY-REN-35 Rho-associated, coiled-coil containing protein kinase 1 Rho-associated, coiled-coil-containing protein kinase 1 Rho-associated, coiled-coil-containing protein kinase I ROCK-I
Product
Specifications
Ordering Information
Human
IP
Between 400 and 450
100
$339
$99
Human
WB, IP
Between 550 and 600
100
$339
$229
$99
Human, Mouse
WB, IP
Between 1300 and C-term
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A300-455A, A300-456A and A300-457A
$707
Includes: 1 each of A300-455A, A300-456A and A300-457A