PSMC6 Antibody

Proteasome (prosome, macropain) 26S subunit, ATPase, 6 (PSMC6) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMC6 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity [taken from NCBI Entrez Gene (Gene ID: 5706)].
PSMC6
proteasome 26S subunit, ATPase 6
26S protease regulatory subunit 10B
:  26S protease regulatory subunit S10B 26S proteasome AAA-ATPase subunit RPT4 CADP44 conserved ATPase domain protein 44 epididymis secretory protein Li 73 HEL-S-73 p42 P44 proteasome (prosome, macropain) 26S subunit, ATPase, 6 proteasome 26S subunit ATPase 6 proteasome subunit p42 SUG2 More... Less...
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 275 and 325
100
$339
$99
Human, Mouse
WB, IP, IHC-P
Between 339 and 389
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A303-824A and A303-825A
$472
Includes: 1 each of A303-824A and A303-825A