PAK2 Antibody

PAK2 (p21-activated kinase 2) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. The PAK family of proteins mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins Cdc42 and Rac. PAK2 has been shown to play a specific role in apoptosis and cytoskeletal dynamics. During caspase-mediated apoptosis, PAK2 is cleaved and the C-terminal myristoylated fragment mediates cell death and actin reorganization via the JNK signaling pathway.
PAK2
p21 (RAC1) activated kinase 2
Serine/threonine-protein kinase PAK 2
:  gamma-PAK p21 (CDKN1A)-activated kinase 2 p21 protein (Cdc42/Rac)-activated kinase 2 p21-activated kinase 2 p58 PAK-2 PAK65 PAKgamma S6/H4 kinase
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 25 and 75
$339
$229
$99
Human
WB, IP
Between 125 and 175
$339
$229
$99
Human, Mouse
Includes: 1 each of A301-263A and A301-264A
$472
Includes: 1 each of A301-263A and A301-264A