NEDD4L Antibody

NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5 [taken from the Universal Protein Resource (UniProt) wwwuniprotorg/uniprot/Q96PU5].
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
E3 ubiquitin-protein ligase NEDD4-like
:  hNEDD4-2 KIAA0439 NEDD4.2 NEDD4-2 neural precursor cell expressed, developmentally down-regulated 4-like RSP5 ubiquitin-protein ligase Rsp5
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 225 and 275
$339
$229
$99
Human, Mouse
WB, IP, IHC-P
Between 275 and 325
$339
$229
$99
Human, Mouse
WB, IP
Between 425 and 475
$339
$229
$99
Human, Mouse
Includes: 1 each of A302-512A, A302-513A and A302-514A
$707
Includes: 1 each of A302-512A, A302-513A and A302-514A
Human, Mouse
IHC-P
Between 275 and 325
$360
$99