DYRK1A Antibody

Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. DYRK1A contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome [taken from NCBI Entrez Gene (Gene ID: 5201)].
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
:  dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A dual specificity YAK1-related kinase dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DYRK DYRK1 hMNB HP86 MNB mnb protein kinase homolog hp86 MNB/DYRK protein kinase MNBH MRD7 protein kinase minibrain homolog serine/threonine kinase MNB serine/threonine-specific protein kinase More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 25 and 50
100
$339
$229
$99
Human
WB, IP
Between 713 abd 763
100
$339
$229
$99
Human
100
Includes: 1 each of A303-801A and A303-802A
$472
Includes: 1 each of A303-801A and A303-802A