A20 Antibody

Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21580].
TNFAIP3
TNF alpha induced protein 3
Tumor necrosis factor alpha-induced protein 3
:  A20 AISBL OTU domain-containing protein 7C OTUD7C putative DNA-binding protein A20 TNF alpha-induced protein 3 TNFA1P2 tumor necrosis factor inducible protein A20 tumor necrosis factor, alpha induced protein 3 tumor necrosis factor, alpha-induced protein 3 zinc finger protein A20 More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 525 and 575
$339
$229
$99