Astrin/MAP126 Antibody

Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
SPAG5
sperm associated antigen 5
Sperm-associated antigen 5
:  astrin DEEPEST hMAP126 MAP126 mitotic spindle associated protein p126 mitotic spindle coiled-coil related protein mitotic spindle-associated protein p126
Product
Specifications
Ordering Information
Human
IP
Between 1 and 50
100
$339
$99
Human
WB, IP
Between 875 and 925
100
$339
$229
$99
Human
100
Includes: 1 each of A301-511A and A301-512A
$472
Includes: 1 each of A301-511A and A301-512A