UFD1 Antibody

Ubiquitin fusion degradation protein 1 homolog (UFD1) forms a dimer with Npl4 (nuclear protein localization 4) and can associate with the ATPase, p97/VCP, to form a ternary complex involved in the ubiquitin-proteasome pathway. The UFD1-p97-Npl4 complex functions to recognize ubiquitin-tagged proteins and facilitate their presentation to the 26S proteasome for degradation. This ternary complex has also been shown to play an important role in mitotic spindle disassembly. Hemizygosity in the gene which encodes UFD1 (UFD1L) is the cause of some catch 22-associated developmental defects. Additionally, the UFD1L gene has also been implicated in the neurodevelopment al origin of schizophrenia.
UFD1L
ubiquitin fusion degradation 1 like (yeast)
Ubiquitin fusion degradation protein 1 homolog
:  UB fusion protein 1 ubiquitin fusion degradation 1-like UFD1
Product
Specifications
Ordering Information
Human
WB, IP
Between 175 and 225
$339
$229
$99
Human
WB, IP
Between 257 and 307
$339
$229
$99
Human
Includes: 1 each of A301-875A and A301-876A
$472
Includes: 1 each of A301-875A and A301-876A