Treslin Antibody

Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z2Z1].
TICRR
TOPBP1 interacting checkpoint and replication regulator
Treslin
:  C15orf42 chromosome 15 open reading frame 42 FLJ41618 MGC45866 SLD3 SLD3 homolog (S. cerevisiae) TOPBP1-interacting checkpoint and replication regulator TOPBP1-interacting replication-stimulating protein topBP1-interacting, replication-stimulating protein Treslin More... Less...
Product
Specifications
Ordering Information
Human
WB
Between 975 and 1025
100
$339
$229
$99