PSMD1 Antibody

PSMD1 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 1] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD1 is the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5707)].
PSMD1
proteasome 26S subunit, non-ATPase 1
26S proteasome non-ATPase regulatory subunit 1
:  26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit S1 26S proteasome subunit p112 P112 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 Rpn2 S1
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 1 and 50
$339
$229
$99
Human, Mouse
WB, IP, IHC-P
Between 903 and 953
$339
$229
$99
Human, Mouse
Includes: 1 each of A303-851A and A303-852A
$472
Includes: 1 each of A303-851A and A303-852A