MCAK Antibody

Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.
KIF2C
kinesin family member 2C
Kinesin-like protein KIF2C
:  4930402F02Rik CT139 ESTM5 kinesin-like 6 kinesin-like 6 (mitotic centromere-associated kinesin) kinesin-like protein 6 KNSL6 MCAK mitotic centromere-associated kinesin testis tissue sperm-binding protein Li 68n X83316
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 50 and 100
100
$339
$99
Human
WB, IP
Between 550 and 600
100
$339
$229
$99
Human
WB, IP
Between 675 and C-term
100
$339
$229
$99
Mouse
WB, IP, IHC-P
Between 50 and 100
100
$339
$229
$99
Mouse
IP
Between 550 and 600
100
$339
$99
Human
100
Includes: 1 each of A300-806A, A300-807A and A300-808A
$707
Includes: 1 each of A300-806A, A300-807A and A300-808A
Mouse
100
Includes: 1 each of A300-921A and A300-922A
$472
Includes: 1 each of A300-921A and A300-922A
Human
IHC-P
Between 50 and 100
100
$360
$99
Mouse
IHC-P
Between 50 and 100
100
$360
$99