Charged multivesicular body protein 3 (CHMP3) is a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. CHMP3 may also co-immunoprecipitate with a member of the IFG-binding protein superfamily [taken from NCBI Entrez Gene (Gene ID: 51652)].
CHMP family, member 3•
chromatin-modifying protein 3•
neuroendocrine differentiation factor•
vacuolar protein sorting 24 (yeast)•
vacuolar protein sorting 24 homolog•
vacuolar protein sorting 24 homolog (S. cerevisiae)•
vacuolar protein sorting-associated protein 24•