Sirt6 Antibody

Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N6T7].
SIRT6
sirtuin 6
NAD-dependent protein deacetylase sirtuin-6
:  regulatory protein SIR2 homolog 6 SIR2L6 SIR2-like protein 6 sir2-related protein type 6 sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6 sirtuin type 6 More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 50 and 100
100
$339
$99
Human
WB, IP
Between 305 and 355
100
$339
$229
$99
Human
100
Includes: 1 each of A302-451A and A302-452A
$472
Includes: 1 each of A302-451A and A302-452A