BRCA2 Antibody

BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar; however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1.
BRCA2
BRCA2, DNA repair associated
Breast cancer type 2 susceptibility protein
:  BRCA1/BRCA2-containing complex, subunit 2 BRCC2 breast and ovarian cancer susceptibility gene, early onset breast and ovarian cancer susceptibility protein 2 breast cancer 2 tumor suppressor breast cancer 2, early onset BROVCA2 FACD FAD FAD1 FANCD FANCD1 Fanconi anemia group D1 protein Fanconi anemia, complementation group D1 GLM3 mutant BRCA2 PNCA2 XRCC11 More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 3350 and C-term
100
$339
$229
$99
Human
WB, IP
Between 450 and 500
100
$339
$229
$99
Human
IP
Between 2850 and 2900
100
$339
$99
Human
IP
Between 3350 and C-term
100
$356
Human
100
Includes: 1 each of A303-434A and A303-435A
$472
Includes: 1 each of A303-434A and A303-435A