p53 Antibody

p53 is a tumor suppressor protein that is mutated or inactivated in over 50% of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.
TP53
tumor protein p53
Cellular tumor antigen p53
:  antigen NY-CO-13 BCC7 LFS1 Li-Fraumeni syndrome mutant tumor protein 53 p53 p53 tumor suppressor phosphoprotein p53 transformation-related protein 53 TRP53 tumor protein 53 Tumor suppressor p53 tumor supressor p53
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P, IF, ChIP-Seq, PLA, F
Between 50 and 100
$339
$229
$99
Human
WB, IP
Between 325 and 375
$339
$229
$99
Human
WB, IP, IHC-P
Between 375 and C-term
$339
$229
$99
Human
Includes: 1 each of A300-247A, A300-248A and A300-249A
$707
Includes: 1 each of A300-247A, A300-248A and A300-249A
Human
IHC-P
Between 50 and 100
$360
$99
Human
WB, IP, IHC-P
Recombinant full length protein corresponding to Human p53 (N terminal). epitope is within aa 20-25
$229
$99