TAB2 Antibody

TAB2 (TGF-beta-activated kinase 1and MAP3K7-binding protein 2) functions as an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. TAB2 forms a kinase complex with TRAF6, MAP3K7 and TAB1, and thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts [taken from NCBI Entrez Gene (GeneID: 23118)].
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
:  CHTD2 KIAA0733 MAP3K7IP2 mitogen-activated protein kinase kinase kinase 7 interacting protein 2 mitogen-activated protein kinase kinase kinase 7-interacting protein 2 TAB-2 TAK1-binding protein 2 TGF-beta-activated kinase 1-binding protein 2
Product
Specifications
Ordering Information
Human
IP
Between 300 and 350
100
$339
$99
Human, Mouse
WB, IP
Between 500 and 550
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A302-758A and A302-759A
$472
Includes: 1 each of A302-758A and A302-759A