Junctophilin-2 Antibody

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Junctophilins provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. Junctophilin-2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release, and contributes to the construction of skeletal muscle triad junctions [Taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BR39].
JPH2
junctophilin 2
Junctophilin-2
:  CMH17 JP2 JP-2 junctophilin type 2
Product
Specifications
Ordering Information
Human
WB, IP
Between 625 to 675
$339
$229
$99