Notch1 Antibody

Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.
NOTCH1
notch 1
Neurogenic locus notch homolog protein 1
:  AOS5 AOVD1 hN1 Notch (Drosophila) homolog 1 (translocation-associated) Notch 1 Notch homolog 1, translocation-associated Notch homolog 1, translocation-associated (Drosophila) TAN1 translocation-associated notch protein TAN-1
Product
Specifications
Ordering Information
Human
IP, PLA
Between 2400 and 2450
$339
$99
Human
WB, IP, IHC-P
Between 2505 and 2555
$339
$229
$99
Human
Includes: 1 each of A301-894A and A301-895A
$472
Includes: 1 each of A301-894A and A301-895A
Human
IHC-P
Between 2505 and 2555
$360
$99