NF1 Antibody

Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.
NF1
neurofibromin 1
Neurofibromin
:  neurofibromatosis neurofibromatosis-related protein NF-1 NFNS von Recklinghausen disease VRNF Watson disease WSS
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 2760 and C-term
100
$339
$229
$99
Human
IP
Between 1 and 50
100
$339
$99
Human
IP
Between 150 and 200
100
$339
$99
Human
100
Includes: 1 each of A304-931A and A304-932A
$472
Includes: 1 each of A304-931A and A304-932A