p600 Antibody

p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T4S7].
UBR4
ubiquitin protein ligase E3 component n-recognin 4
E3 ubiquitin-protein ligase UBR4
:  600 kDa retinoblastoma protein-associated factor KIAA0462 KIAA1307 N-recognin-4 p600 RBAF600 retinoblastoma-associated factor 600-like protein retinoblastoma-associated factor of 600 kDa zinc finger UBR1-type protein 1 zinc finger, UBR1 type 1 ZUBR1
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 150 and 200
100
$339
$99
Human, Mouse
WB, IP, IHC-P
Between 1350 and 1400
100
$339
$229
$99
Human
WB, IHC-P
Between 5133 and 5183
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A302-277A, A302-278A and A302-279A
$705
Includes: 1 each of A302-277A, A302-278A and A302-279A
Human
IHC-P, IF
Between 5133 and 5183
100
$360
$99