Presenilin-2 Antibody

Presenilin-2 is a probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Presenilin-2 requires the other members of the gamma-secretase complex to have a protease activity. It may play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may function in the cytoplasmic partitioning of proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49810].
PSEN2
presenilin 2
Presenilin-2
:  AD3L AD3LP AD4 AD5 Alzheimer disease 4 CMD1V E5-1 PS2 PS-2 STM2 STM-2
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 275 to 325
100
$339
$229
$99