PHLPPL Antibody

PHLPPL (PH domain leucine-rich repeat-containing protein phosphatase-like) is responsible for the dephosphorylation and subsequent inactivation of Akt. Akt is a signaling protein critical to the balance of cell survival and apoptosis. Dephosphorylation of Akt by PHLPPL has been demonstrated to trigger apoptosis and suppress tumor cell growth. PHLPPL is also known as PHLPPL2 and functions similarly to its relative, PHLPP1. Recent studies show that PHLPPL and PHLPP selectively terminate Akt-signaling by targeting specific Akt isoforms.
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
PH domain leucine-rich repeat-containing protein phosphatase 2
:  KIAA0931 PH domain and leucine rich repeat protein phosphatase-like PH domain leucine-rich repeat-containing protein phosphatase-like PHLPPL PHLPP-like PPM3B protein phosphatase, Mg2+/Mn2+ dependent 3B
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 1275 and C-term
$339
$229
$99