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Search Results for "PBRM1"

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Rabbit anti-PBRM1 Antibody
Bethyl Laboratories® Catalog # A301-591A-T A301-591A

Validated

Rabbit anti-PBRM1 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (11) Citations ()

Target: PBRM1

Reactivity: Human, Mouse

Applications:

Platforms: PhenoImager™ HT

Host: Rabbit

Conjugate:

Purity:

6 Figures

parentCodeBETHYL-A301-591

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For ordering information, see our International Distributors

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Product has been discontinued
Rabbit anti-PBRM1 Antibody
Bethyl Laboratories® Catalog # A301-590A-T A301-590A

Validated

Rabbit anti-PBRM1 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (4) Citations ()

Target: PBRM1

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-A301-590

Bulk Request

For ordering information, see our International Distributors

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Product has been discontinued
Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]
Bethyl Laboratories® Catalog # A700-019-T A700-019 A700-019CF

Validated

Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]

Validation Performed

Pillar 1: Independent Antibodies
Pillar 2: Complementary Assays
Pillar 4: Biological Characteristics

Learn more about the validation performed

Documents (13) Citations ()

Target: PBRM1

Reactivity: Human, Mouse

Applications:

Platforms: COMET™, PhenoImager™ HT, Simple Western

Host: Rabbit

Conjugate:

Purity:

8 Figures

parentCodeBETHYL-A700-019

Bulk Request

For ordering information, see our International Distributors

Distributors

Product has been discontinued

The Many Sides of PBRM1
Whitepaper

Polybromo protein 1, also known as PBRM1, is a promising biomarker for immune checkpoint inhibitor therapy. Find out more about this gene and its potential to change the future of cancer treatment.
PBRM1 Joins p53 To Impact Kidney Cancer
Jessica J. DeWitt, Ph.D.

Article

p53 is a well-known tumor suppressor protein which suppresses cancer by regulating the cell cycle. It is encoded by the gene, TP53. A key component of p53’s suppressor activity is modulated through post-translational modifications, namely acetylation. Acetylation patterns of p53 help determine the protein’s function. These acetylation patterns can be "written," "erased," and "read." "Writing" refers to the addition of acetyl groups by enzymes like histone acetyltransferases, and "Erasing" refers to the removal of acetyl groups by enzymes like histone deacetylases. "Readers" recognize and bind to the acetyl groups on the p53 protein and can inhibit or enhance p53 transcription.

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