LYN Antibody

LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. It is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07948].
LYN
LYN proto-oncogene, Src family tyrosine kinase
Tyrosine-protein kinase Lyn
:  JTK8 lck/Yes-related novel protein tyrosine kinase p53Lyn p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Product
Specifications
Ordering Information
Human
WB, IP
Between 1 and 50
$339
$229
$99